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Pregnancy
Introducation
Pregnancy occurs when an egg is fertilized by a sperm, grows, and develops into a baby. In humans, this takes about 280 days.
  • Definitions
    • Intra-uterine pregnancy: A normal pregnancy occurs when a fertilized egg is implanted within the uterus (womb) and an embryo grows.
    • Ectopic pregnancy: An abnormal pregnancy in which the egg implants outside of the uterus. This can be life-threatening. Ectopic pregnancy must be diagnosed early to avoid damage to the tubes and prevent serious illness or death in the mother. It is also called tubal pregnancy or extra-uterine pregnancy.
    • Beta human chorionic gonadotropin (also called hCG-beta): This hormone is secreted by the placenta and can be measured to determine the presence and progression of pregnancy. It can be tested in urine or blood and is the hormone measured by a home pregnancy test. Positive means pregnant. This test can stay positive for several weeks after delivering a baby or after a miscarriage.
    • High-risk pregnancy: This refers to a woman who is more likely to have complications. Examples include women with diabetes and high blood pressure.
    • Trimester: A pregnancy is divided into 3 sections or trimesters. Each trimester has particular events and developmental markers. For instance, the first trimester builds the foundation of the different organ systems.
    • Pre-eclampsia/eclampsia: This condition causes a woman's blood pressure to rise, her body to swell, and her nervous reflexes to change. If untreated, pre-eclampsia can lead to eclampsia, which is a serious illness causing seizures, coma, and even death.
    • Estimated date of confinement (EDC): The delivery date is estimated by counting forward 280 days from the first day of the last period. It is also called the estimated date of delivery (EDD).
    • Embryo: The developing fertilized egg during the first 12 weeks of pregnancy is an embryo.
    • Fetus: After 12 weeks of gestation, the developing embryo is called a fetus.
Signs & Symptoms
Signs and symptoms of pregnancy include the following:
  • Breast tenderness
  • Nausea or vomiting or both
  • Missing a period or having an abnormal period
  • Weight gain
  • Passing urine more frequently than usual
Home Care
If you suspect that you are pregnant or have a positive home-pregnancy test, make an appointment with your family doctor, obstetrician, midwife, or nurse practitioner.
  • Eat small, frequent meals throughout your pregnancy. Eat a common-sense balanced diet. Expect to gain between 25 and 35 pounds.
  • Don't take medicines that you don't need.
  • Don't smoke, drink alcohol, or use street drugs.
When to Call The Doctor
Call a doctor or midwife if any of the following conditions develop:
  • Have abdominal or vaginal pain
  • Vomit more than 3 times a day
  • Find your blood pressure is elevated severely above 140/90
  • Experience a sudden and rapid weight gain
  • Develop a severe headache or changes in your vision
When to Go To The Hospital
  • If you pass pink, gray, or white material from your vagina that does not look like a blood clot, you should see a doctor.
  • If you have a bloody discharge or gush of water from your vagina, you may be going into labor and should see a doctor.
  • If you have lower abdominal pain late in pregnancy, they may be labor pains, which are contractions of the uterus. You should see a doctor.
  • If you have a seizure and do not have a history of epilepsy, you may have eclampsia (a complication of pregnancy), and you should see a doctor.
  • If you have an injury, such as a fall, a blow to your stomach or pelvis, or a car wreck, you should see a doctor.
Physician Diagnosis
  • Pregnancy tests: Your urine or blood may be tested.
  • Ultrasound: Your doctor may use sound waves to examine your internal structures such as your uterus, ovaries, and the embryo or fetus.
    • Transabdominal: A jelly is put on your abdomen and a sound-wave wand is moved around to look into your pelvis. Your bladder must be full to help transmit the sound waves. This method works best later in pregnancy when the fetus is well developed.
    • Endovaginal or transvaginal: A long thin sound-wave wand is covered with a condom and put inside your vagina. This type of ultrasound is usually done early in pregnancy to make sure that the embryo or fetus is inside the uterus where it belongs.
Physician Treatment
Normal pregnancy is not an illness and needs no "treatment." If your pregnancy is difficult or complicated, your treatment can vary from simple bedrest to amniocentesis, which is removal of amniotic fluid from the sac surrounding the pregnancy for testing, or a stay in the hospital.

Because so many medicines can hurt your pregnancy, it is extremely important that you take only medicines that have been approved by your doctor or midwife. If anyone tries to prescribe a new medicine, remind them that you are pregnant and ask if it's safe to take.

  • The Food and Drug Administration (FDA) lists 5 categories of labeling for drug use in pregnancy.
    • Category A - Safety has been established using human studies
    • Category B - Presumed safety based upon animal studies
    • Category C - Uncertain safety with animal studies showing an adverse effect
    • Category D - Unsafe with evidence of risk that may in certain clinical circumstances be justifiable
    • Category X - Highly unsafe with risk or use outweighing any possible benefit
  • Electronic fetal monitoring: Sometimes late in pregnancy, you may be placed on a fetal monitor to verify the health of the fetus or to see if you are in early labor.
Prognosis
Many events determine the outcome of a pregnancy.
  • Maternal weight gain: The amount of weight you gain can be important in predicting a normal pregnancy.
  • Nausea and vomiting: Even if you have what seems like an abnormal amount of nausea and vomiting, it probably won't affect your baby's health.
  • Maternal diabetes (types 1 and 2): If you have diabetes or develop diabetes during pregnancy, it can cause early labor, birth defects, and very large babies.
  • Low or high red blood cell counts: Your risk of having a premature baby is increased if your blood count is low (anemia). If your blood count is too high (polycythemia), your baby may be smaller than expected.
  • Maternal obesity: If you are obese and have diabetes, you are 3 times more likely to have a baby with a birth defect. If you are obese but do not have diabetes, your risk of birth defects is not increased.
  • Maternal age: If you are older than 35 years, you have a higher risk of birth defects and complications
Prevention
Preventing pregnancy is called contraception. There are many ways to prevent pregnancy, but none of them is 100% effective. An ideal contraceptive would be 100% effective, 100% convenient, 100% reversible, 100% safe, socially acceptable, cheap, and easy to use.
  • Sterilization - Male (vasectomy) or female (tubal ligation)
  • Subcutaneous implant - Medication put under the skin, such as Norplant
  • Intra-uterine device (IUD)
  • Diaphragm
  • Condoms
  • Spermicides
  • Coitus interruptus - Withdrawal by male before climax
  • Rhythm method - Not having sex during time when most likely to be fertile
  • Abstinence - No sexual intercourse

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