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Headache

Overview

One of the most common afflictions among all people, headache strikes nearly everyone at some point in life. While many of these painful episodes are transitory, experts estimate that up to 90% of all people - as many as 50 million persons in the United States alone - suffer some form of recurrent or chronic headache in their lifetime. Many of these attacks are severe enough to disrupt daily activities. An estimated 8 million persons a year visit their doctors with headache complaints, and the cost in terms of lost productivity, not to mention diminished quality of life, may be beyond our ability to compute.

Headache Classification
The International Headache Society (IHS) has developed a detailed sytem to categorize different types of headache. The initial division focuses on the three primary forms of headache: migraine, tension type headache, and cluster headache. These are then subdivided within each group, because headaches can vary in presentation significantly from one individual to another. The IHS then attempted to describe other forms of headache that may have an identifiable etiology and that are different from the three primary headache types. These include headache associated with cerebrovascular disease, head trauma, infection, tumors, medications, and metabolic abnormalities(e.g., diabetes, thyroid conditions, hormonal changes). In addition, there are syndromes that can result in head pain involving other structures of the head, face, and neck. These may include pain in the eyes, ears, neck, teeth, or sinuses.

Causes

While there are several different types of headache, each of which may vary in severity, frequency, cause, and symptoms, many experts generally classify them as primary or secondary.

Primary headaches are those not associated with an underlying medical condition. They account for about 90% of all headaches, of which the three most common are migraines, cluster, and tension-type headaches.

Some primary headaches have known causes, such as stress, muscular tension, vascular dilation, postural changes, protracted coughing or sneezing, and fevers. Others, such as migraines, seem to be triggered by factors varying from diet to the menstrual cycle to exposure to sunlight. How these triggers produce pain is still not well understood.

Secondary headaches are those associated with an underlying medical condition, such as infection, injury to the head, and increased pressure within the skull caused by a tumor.

Anatomy: Where does the pain come from?
Headache pain may be confined to a single area or may be felt in multiple areas of the head, face, mouth, throat, and neck. In all cases, however, headache pain derives from the network of nerve fibers in the tissues, muscles, and blood vessels located in the head and at the base of the brain. Interestingly, brain tissue itself has no nerve fibers and consequently is impervious to pain.

When stimulated by stress, tension, and other factors, the ends of these nerve fibers, or nociceptors, generate electrochemical signals that travel up the nerve network to the brain, where they are interpreted as pain in the point of origin. Some of these neurological signals include natural painkilling compounds called endorphins. Some researchers believe that people who experience different types of severe or chronic pain, including frequent or profound headaches, may suffer from a lower-than-normal level of endorphins in their body.

Symptoms

Headache symptoms vary considerably from person to person, and from one type of headache to another. A migraine, for example, produces typically unilateral, throbbing pain that can last for days, along with an assortment of secondary symptoms such as nausea, vomiting, flu-like fever, chills and aches, and others. Cluster headaches, by comparison, usually occur on one side of the head only and typically last from a few minutes to a few hours.

Diagnosis

A thorough medical examination and history are necessary in the diagnostic evaluation of the patient complaining of severe headache. This should include an eye exam to check for muscular weakness or pupils of unequal size, detailed questions about the characteristics of the patient's headache, his or her age, sleep habits, family history, and a record of medications being taken.

A neurological examination and laboratory workup of the patient's blood characteristics and thyroid, liver, and kidney functions also may be recommended. In some cases, imaging studies of the brain may be performed to rule out brain tumors, stroke, infections, vascular malformations such as aneurysms, and other disorders. Such studies may include:

  • an EEG (electroencephalogram) to measure brain activity;
  • a CAT (computer axial tomography) or MRI (magnetic resonance imaging) scan to examine the tissues and structures around, on, and in the brain; or
  • head x-rays, an MRA (magnetic resonance angiography) to check the brain's blood vessels.

Treatment

Many people obtain headache relief through medication. These treatments can be divided into two broad categories. Symptomatic medication is taken at the time of the headache to treat the symptoms, and prophylactic medication is taken on a daily basis to prevent headaches from occurring.

With all analgesic (painkilling) medications, it is important to guard against overuse. Excessive consumption of analgesics can result in drug rebound headache, a condition in which high levels of the drug in the patient's system actually cause daily headaches. In most cases, patients with rebound headaches, particularly those taking medication on a prophylactic basis, experience improvement when their daily medications are stopped, enabling them to obtain greater relief through symptomatic treatment.

Not all headaches require medical treatment. Those resulting from periodic tension or poor eating habits usually can be dealt with successfully through lifestyle adjustments and occasional symptomatic treatment.

Some headaches indicate a more serious underlying condition requiring prompt attention, however. Generally, these secondary headaches are severe, sudden, and debilitating. If they have been precipitated by a blow to the head, if they interfere with normal living, or if they are accompanied by other symptoms - convulsions, disorientation, dizziness, loss of consciousness, pain in the eye or ear, or fever - especially in children or persons who previously were relatively headache-free, patients should see their family physician for a medical examination and evaluation as soon as possible.

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