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Childhood Cancer,
Epidemiology |
For the year 2000,
the prediction stated that 1.2 million new
individuals would be diagnosed with invasive
cancer in the US. Of these, roughly 10,000 were
expected to be ....... |
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Childhood Cancer,
Genetics |
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An important
development in cancer research over the past 2
decades has been the recognition that genetic
changes drive the pathogenesis of tumors of both
adulthood and ......
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Carcinoid Tumor |
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Carcinoids are the
most common neuroendocrine tumors, with clinical
cases estimated to be 1.5 per 100,000 population.
The incidence in autopsy cases is much higher,.... |
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Bone Marrow
Transplantation, Long-Term Effects |
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Many children are
surviving bone marrow transplantation (BMT) and
require long-term follow-up care. The number of
late BMT survivors is expected to increase as new
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Medulloblastoma |
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Medulloblastoma is
the most common malignant brain tumor in children,
accounting for 10-20% of primary central nervous
system (CNS) neoplasms and approximately...... |
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Hodgkin Disease |
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Hodgkin disease
(HD) is a malignant disorder of the lymph node
that is highly curable with combined modality
therapy. Following its first description in 1832
and before the malignant
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Oncologic
Emergencies |
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Four
primary etiologies underlie most emergencies that
occur in the field of pediatric oncology. Each of
the causes may result in an additional emergency,
ie, pain...... |
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Osteosarcoma
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Osteosarcoma is the
third most common cancer in adolescence, occurring
less frequently than only lymphomas and brain
tumors. It is thought to arise from a primitive
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Clear Cell Sarcoma
of the Kidney |
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Clear cell sarcoma
of the kidney (CCSK), an uncommon renal neoplasm
of childhood, represents one of the most common
tumors with “unfavorable histology” listed in the
National .... |
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Acute
Lymphoblastic Leukemia |
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Acute lymphoblastic
leukemia (ALL) is the most common malignancy of
childhood, representing nearly one third of all
pediatric cancers. Annual incidence of ALL is
about 30 cases.... |
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Acute Myelocytic
Leukemia |
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Acute myelogenous
leukemia (AML) is a group of malignant disorders
characterized by the replacement of normal bone
marrow with abnormal, primitive hematopoietic
cells....... |
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Astrocytoma
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Brain tumors
comprise approximately 20% of all childhood
malignancies, second only to acute lymphoblastic
leukemia in frequency. Astrocytoma is the most
common brain tumor..... |
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Gorlin Syndrome
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Gorlin syndrome is
an autosomal dominant cancer syndrome. Patients
with this rare syndrome often have anomalies of
multiple organs, many of which are subtle. Study
of patients ...... |
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Wilms Tumor
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Wilms tumor or
nephroblastoma is the most common childhood
abdominal malignancy. In the past 3 decades, the
multidisciplinary approach to this tumor has
become ..... |
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Tumor Lysis
Syndrome |
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Tumor lysis
syndrome is a very serious and sometimes
life-threatening complication of cancer therapy.
It can be defined as a pattern of metabolic
abnormalities ....... |
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Rhabdoid Tumor
of the Kidney |
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Rhabdoid tumor of
the kidney (RTK) is one of the most aggressive and
lethal malignancies in pediatric oncology. It
initially was described as a rhabdomyosarcomatoid
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